Mebendazole is an effective antiparasitic medication used to treat various intestinal worm infections. Once ingested, it works by interfering with the worms’ ability to absorb glucose, ultimately killing them. But how long does it actually remain in your system after you take it?
After oral administration, Mebendazole is poorly absorbed into the bloodstream, with most of the drug staying in the gastrointestinal tract to act directly on the worms. The small amount that does get absorbed is metabolized by the liver and excreted mainly in the bile and feces, with a smaller portion eliminated through urine.
The elimination half-life of Mebendazole 100 mg is approximately 3 to 6 hours, meaning it takes that amount of time for half the dose to be cleared from your system. Generally, the drug is completely eliminated within 24 to 48 hours after the final dose. However, this duration may vary depending on the dosage, duration of treatment, age, and liver function of the individual.
Because it doesn’t build up in the body, Mebendazole is considered safe for short-term use, and side effects are typically mild and temporary. Even though it clears the system quickly, its effect on the parasites can continue for several days, ensuring thorough treatment.
In conclusion, Mebendazole doesn’t stay in your system for long—typically no more than two days. It’s fast-acting, effective, and widely trusted for treating common intestinal parasites in both children and adults.